How do you deal with Featured Image & Media Queries

Since featured image sets default sizes, example:

add_image_size( ‘post-thumbnails2200px’, 360, 250, true );
add_image_size( ‘post-thumbnails1280px’, 250, 250, true );
add_image_size( ‘post-thumbnails800px’, 150, 250, true );

my question is how do you display featured image with different sizes without using the css max-width or any css styles.

I’m having trouble displaying it when i try on different resolution. actually, i have no idea what to do. when i use css, it gets distorted since the height is fixed in 250px.

i am wondering if you someone could share their php if and else script or javascript or anything. please help!