Hi @cavendishqi,
Thank you for your question.
The “Markdown on Save Improved” supports only posts and pages by default.
To support Custom Post Type which is used in Wiki plugin, you should add following code in the functions.php file of your child theme or add it in your site using any of the following plugins.
add_action( 'init', 'wiki_add_markdown_support' );
function wiki_add_markdown_support(){
add_post_type_support( 'incsub_wiki', 'markdown-osi' );
}
https://www.ads-software.com/plugins/add-actions-and-filters/
https://www.ads-software.com/plugins/code-snippets/
Cheers,