Have you followed basic WordPress troubleshooting procedure?
Disable all plugins and use a default WordPress theme.
Do uploads work now? Great. It means WordPress is working fine.
If things aren’t working as expected then there may be a server configuration issue or perhaps the WP 4.5 update didn’t complete successfully. You can try https://codex.www.ads-software.com/Updating_WordPress#Manual_Update and see if that fixes it. Otherwise its time to contact your hosting for support.
Now if everything is working based on the previous step, enable your theme and try uploading media.
Does it work correctly? If yes, great. If not, contact the theme developer for support as the issue is likely the theme.
Now if everything is working correctly with themes, it’s time to test plugins.
Enable one plugin and test it one at a time – if everything works, move on to the next plugin and enable it. Once you see issues, note which plugin you last enabled and contact the plugin developer for support.
At the end of this process you’ll have figured out what is the culprit behind the media upload issue. Most likely it isn’t WordPress core – it’s either a server configuration issue, a theme that hasn’t been updated to support 4.5, or a plugin that also hasn’t been updated to support 4.5.