Hi @mesmer7, thanks for your question.
My answer is, “sort-of”. In many cases where visits to non-existent paths/URLs are done, they happen with no prior knowledge of the plugins or platform you’re running and are done in a hit-and-hope manner by bots. Making sure your plugins, themes, and WordPress itself are always the latest versions should limit the chance of one of these ever succeeding.
Google and other legitimate bots should mostly only be hitting paths that exist or have existed in the past, but keeping an eye on your Live Traffic blocks should reveal whether any of your manually input URLs are problematic for them. If you see a number of Google (or other search) bots blocked at paths you’ve chosen, it could be worth removing the paths from that setting.
Wordfence itself handles its blocks by looking at the intent of an IP’s visit rather than just the page they tried to visit. The plugin does all of the important blocking for you so it’s our general recommendation to not implement a manual blocking regime – which can be time consuming to keep up with current URLs and IP ranges etc. However, if your site is being hit many times from one specific attack on the same path over and over, I can see why you’d want to stem the flow yourself.
You can read more here: https://www.wordfence.com/help/firewall/options#immediately-block-urls
Thanks,
Peter.