Enable or Disable

Absolutely, yes. You have 2 options to handle this:

– By css: Just hide in on desktop view by media query

@media screen and (min-width: 768px) {
  .pg-loading-screen {
     visibility: hidden !important;
     opatity: 0 !important;
     display: none !important;
  }
}

– By WP Hooks:
You should have a function to check if the user session is desktop device or not, then add a custom filter to your functions.php like this:

add_filter( 'wp_pleasewait_enable', function ($is_enable) {
  if ( is_on_desktop() ) { 
    return false; 
  }
  return $is_enable;
}, 10, 1);