Fatal Error Message….HELP

PLease look into this message and share your insights…

Is there a string to inset?

Warning: require_once(/home/content/52/5151252/html/wp-load.php) [function.require-once]: failed to open stream: No such file or directory in /home/content/52/5151252/html/wp-blog-header.php on line 12

Fatal error: require_once() [function.require]: Failed opening required ‘/home/content/52/5151252/html/wp-load.php’ (include_path=’.:/usr/local/php5/lib/php’) in /home/content/52/5151252/html/wp-blog-header.php on line 12

Thanks for considering my request….