I need some Advice. Can You help?

Hello,

I am Putting plans together to build a site that is a searchable directory of artists, photographers, stylists, and other print media based talent. I would like the search and output after the search to work much like krop.com Except this is wont be a job search site it will be a database for producers and agencies. Is there any theme that you guys know of that is one column with a huge search box at the top? Would WordPress be a decent CMS to operate this type of site? I am thinking I will have to tweak an existing theme. Are there any plugins that you guys know of that would make this task easier? Any advice or tips would be greatly appreciated!
Thank You,
Justin