Making Redirection plugin work in a custom script which uses wp-load.php

We have?a script which handles it’s own URL rewriting. e.g. /test/index.php?page=xyz is rewritten as e.g. /test/xyz

This index.php script uses <?php require 'wp-load.php'; ?> to work behind the scenes. Is it possible to make the Redirection plugin work in such an environments too?

I am currently going through the plugin’s code to figure out how it works and where / if I can hook into the plugin’s features through a custom script.

I could just use .htaccess to do the redirection if this sounds unlikely to you too. But I thought if it was possible to manage it through the plugin it would be easier to manage in the long run.