MS Word Blogging on Self Served domain

I don’t know, but it seems likely since this article explains how to use wordpress.com for hosted blogging:
https://office.microsoft.com/en-us/word/ha101640211033.aspx

Finally found the detailed answer here:
https://www.techmonk.com/post-articles-to-blog-using-ms-word/501/

Note specifically:

Note: If you are using www.ads-software.com (Self-hosted) then you need to enable XML – RPC. (Remote Publishing Client). To do so, go to “Settings- Writing”. Check the Enable Remote Publishing option.