Yes, Index WP MySQL For Speed supports multisite installations. Activate it on the network plugins page, then add the keys for each site separately, from each site’s own Tools / Index MySQL page.
Or, if you have access to WP-CLI and you have, for example, three sites in your multisite instance, you can do this to add the keys to all your sites.
wp index-mysql enable --all --blogid=1
wp index-mysql enable --all --blogid=2
wp index-mysql enable --all --blogid=3
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This reply was modified 2 years, 3 months ago by OllieJones.