WordPress installation on Amazon Web Services; Domain Pointing Assistance

Hello,
This is a 2-part question I think. I need to point a domain name URL to a folder on an Amazon Web Services folder on a main AWS IP address that will be a WP installation. Has anyone used AWS and can let me know what I need todo to fwd/point to the specific folder, and if anything needs tweaked with the WP install – more than usual.

Thanks a lot!