Hello VUpdraft, and thanks for your response.
The issue isn’t coming from WP-SMTP or any other plugin—it’s definitely coming directly from Updraft, 100%.
For now, my solution has been to split the files into 50MB chunks. However, it’s quite difficult to work this way, especially when dealing with a 1-2GB media folder. This results in a lot of ZIP files to upload, but it works.
Do you happen to have any idea about the chunk size? Could there be some server limitations?