I’m seeing the same thing. I installed the Yoast WordPress SEO plugin today so not sure if this is related. It was only while experimenting with the SEO plugin that I noticed Google analytics was starting to register all my hits on the site even though I was logged in as an Administrator.
I checked the GA plugin and saw the Administrators were no longer listed in the Ignore Users field. When I tried adding them back I get the same error message that no changes have been made.
Any ideas?