No idea what’s behind this. I have had a problem in the past with plug-ins that call other sites. I have to add the IP address of the target site to the server firewall… wondering if I may need to add a Facebook IP address to the firewall, but that’s a long-shot.
Standard install of 3.3.2 – Not a multi-site.
FWIW – Other installed plug-ins are: After The Deadline, Akismet, All-in-One SEO, Feedburner Feedsmith, Google XML Sitemaps, WordPress.com Stats, WP to Twitter and WPTouch