I’m testing this at the moment. Hope it works fine with SuperCache plug-in ! (if yes, then maybe this is the only anti spam plug-in that works with wp-supercache besides Akismet and WP-SpamFree)
EDIT: I guess not.. I got an error Error: please fill the required fields (name, email)., even though I’ve put them on (I was using the automated template change from the setting)