I had the same issue, and IT WAS the update to WP 4.4 caused it. I had two copies of the site to compare before and after update. With WP_DEBUG turned on I had the following notice:
Notice: convert_to_screen(), add_meta_box() was called incorrectly. Likely direct inclusion of wp-admin/includes/template.php in order to use add_meta_box(). This is very wrong. Hook the add_meta_box() call into the add_meta_boxes action instead.
I’d bet the problem lies in here, hopefully there will be a patch soon!